Tuks, United in Pretoria derby
Clifford Mulenga, SuperSport
The University side got their league campaign off to a positive start with a 1-1 home draw against Maritzburg United, though they will feel they should have taken all three points on offer.
The PSL rookies then racked up their first win in the top flight by defeating Golden Arrows 1-0 in Durban in their last outing.
AmaTuks are placed sixth on the league standings after the first two rounds of matches.
SuperSport began their league season with a respectable 1-1 draw away to Ajax Cape Town in the Mother City.
They then headed upcountry and held reigning champions Orlando Pirates to a goalless draw in a home match staged in Polokwane.
Matsatsantsa are placed 11th on the league standings after the first two rounds of matches.
Though University of Pretoria and SuperSport United have played against one another in friendlies in the past, this will be their first top flight league meeting.